KEGG   Mus musculus (house mouse): 15185
Entry
15185             CDS       T01002                                 
Symbol
Hdac6, Hd6, Hdac5, Sfc6, mHDA2
Name
(RefSeq) histone deacetylase 6
  KO
K11407  histone deacetylase 6 [EC:3.5.1.98]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04613  Neutrophil extracellular trap formation
mmu05014  Amyotrophic lateral sclerosis
mmu05034  Alcoholism
mmu05203  Viral carcinogenesis
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    15185 (Hdac6)
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    15185 (Hdac6)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    15185 (Hdac6)
  09165 Substance dependence
   05034 Alcoholism
    15185 (Hdac6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:mmu01009]
    15185 (Hdac6)
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:mmu03019]
    15185 (Hdac6)
   04131 Membrane trafficking [BR:mmu04131]
    15185 (Hdac6)
   03036 Chromosome and associated proteins [BR:mmu03036]
    15185 (Hdac6)
Enzymes [BR:mmu01000]
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.1  In linear amides
    3.5.1.98  histone deacetylase
     15185 (Hdac6)
Protein phosphatases and associated proteins [BR:mmu01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     15185 (Hdac6)
Messenger RNA biogenesis [BR:mmu03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   mRNA cycle factors
    Stress granule specific factors
     15185 (Hdac6)
Membrane trafficking [BR:mmu04131]
 Autophagy
  Aggrephagy
   Other aggrephagy associated proteins
    15185 (Hdac6)
Chromosome and associated proteins [BR:mmu03036]
 Eukaryotic type
  Histone modification proteins
   HDACs (histone deacetylases)
    Class II HDACs
     15185 (Hdac6)
SSDB
Motif
Pfam: Hist_deacetyl zf-UBP zf-UBP_var
Other DBs
NCBI-GeneID: 15185
NCBI-ProteinID: NP_001123888
MGI: 1333752
Ensembl: ENSMUSG00000031161
UniProt: Q9Z2V5
Position
X:complement(7796355..7814284)
AA seq 1149 aa
MTSTGQDSSTRQRKSRHNPQSPLQESSATLKRGGKKCAVPHSSPNLAEVKKKGKMKKLSQ
PAEEDLVVGLQGLDLNPETRVPVGTGLVFDEQLNDFHCLWDDSFPESPERLHAIREQLIL
EGLLGRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLAETYDSVYLHPNSY
SCACLATGSVLRLVDALMGAEIRNGMAVIRPPGHHAQHNLMDGYCMFNHLAVAARYAQKK
HRIQRVLIVDWDVHHGQGTQFIFDQDPSVLYFSIHRYEHGRFWPHLKASNWSTIGFGQGQ
GYTINVPWNQTGMRDADYIAAFLHILLPVASEFQPQLVLVAAGFDALHGDPKGEMAATPA
GFAHLTHLLMGLAGGKLILSLEGGYNLRALAKGVSASLHTLLGDPCPMLESCVVPCASAQ
TSIYCTLEALEPFWEVLERSVETQEEDEVEEAVLEEEEEEGGWEATALPMDTWPLLQNRT
GLVYDEKMMSHCNLWDNHHPETPQRILRIMCHLEEVGLAARCLILPARPALDSELLTCHS
AEYVEHLRTTEKMKTRDLHREGANFDSIYICPSTFACAKLATGAACRLVEAVLSGEVLNG
IAVVRPPGHHAEPNAACGFCFFNSVAVAARHAQIIAGRALRILIVDWDVHHGNGTQHIFE
DDPSVLYVSLHRYDRGTFFPMGDEGASSQVGRDAGIGFTVNVPWNGPRMGDADYLAAWHR
LVLPIAYEFNPELVLISAGFDAAQGDPLGGCQVTPEGYAHLTHLLMGLAGGRIILILEGG
YNLASISESMAACTHSLLGDPPPQLTLLRPPQSGALVSISEVIQVHRKYWRSLRLMKMED
KEECSSSRLVIKKLPPTASPVSAKEMTTPKGKVPEESVRKTIAALPGKESTLGQAKSKMA
KAVLAQGQSSEQAAKGTTLDLATSKETVGGATTDLWASAAAPENFPNQTTSVEALGETEP
TPPASHTNKQTTGASPLQGVTAQQSLQLGVLSTLELSREAEEAHDSEEGLLGEAAGGQDM
NSLMLTQGFGDFNTQDVFYAVTPLSWCPHLMAVCPIPAAGLDVSQPCKTCGTVQENWVCL
TCYQVYCSRYVNAHMVCHHEASEHPLVLSCVDLSTWCYVCQAYVHHEDLQDVKNAAHQNK
FGEDMPHSH
NT seq 3450 nt   +upstreamnt  +downstreamnt
atgacctccaccggccaagattcttctactagacagcgaaagagtaggcacaatccccag
tcaccccttcaggaatccagcgccaccttgaagcgtggtggaaagaagtgtgctgtaccc
cactccagccccaatctagcggaggtaaagaagaaaggcaaaatgaagaagctgagccaa
ccagctgaagaggacctagttgtggggcttcaagggctggatctgaaccctgagacaaga
gtgccagttggtactggattggtgtttgatgaacaactaaatgacttccattgcctttgg
gatgacagcttccctgaaagccctgagcggctccatgccatcagagagcaactgatcctg
gagggcctcctgggccgctgtgtgtcctttcaggcccggttcgctgagaaggaggagctg
atgttggttcacagcctggaatacattgatctgatggagacaacccagtacatgaatgaa
ggggagcttcgagtactggcagaaacctatgattcagtgtatctgcatccgaactcatat
tcctgtgcctgcctggctacaggctctgtcctccggctggtagatgcactcatgggggct
gagattcggaatggcatggccgtcatcaggcctcctggacaccatgctcagcacaatctt
atggatgggtattgcatgttcaaccatctggctgtggctgcccgctatgcgcaaaagaag
caccgcattcagagggttctcatcgtggactgggatgtgcaccatggtcaaggaacacag
ttcatcttcgaccaggaccccagtgtcctttatttctccatccaccgatatgaacatggt
cgcttctggccccaccttaaggcttctaactggtccactataggttttggccaaggccaa
ggatataccatcaatgtaccttggaaccagacgggcatgcgggacgctgactacattgct
gctttcctgcacatcctgctgccagttgcctcggagtttcagcctcaactggtcttggtg
gccgctggatttgatgccctccacggagaccccaagggagagatggctgccacgccagca
ggatttgcccacctaacccatttgctcatgggtttggcaggaggcaagttgattctgtcc
ctggagggtggctataacctccgtgccctggctaagggagtcagtgcttcactccacacc
cttcttggagacccttgccccatgctggagtcctgtgttgtaccttgtgcaagcgcccag
acttccatctactgcactctagaagcccttgaacccttctgggaggtcctggagagatca
gttgagacccaggaggaagatgaagtggaagaagccgtgctagaagaggaggaggaggaa
ggtggctgggaggccactgcactgcccatggatacatggccactgctccagaaccgcact
gggctggtctatgatgagaagatgatgagtcactgcaacctctgggacaatcatcaccct
gagacacctcagcgcatcttacgcatcatgtgtcacctggaggaggtgggccttgcggct
cgctgtctcatcctacctgctcggcctgccctggactctgagctccttacctgccacagt
gctgagtacgtggagcatctccgcaccacagaaaagatgaaaacccgggatctgcaccgt
gaaggtgccaactttgactccatctacatctgccccagcacctttgcctgcgcaaagctt
gccacaggcgctgcctgccgcctggtggaagctgtgctctcgggagaggttctaaatggc
attgcagtagtgcgccctccaggacaccacgcggagccaaatgctgcctgtggtttctgc
tttttcaactcagtagctgtagctgctcgccatgcccagatcattgctggacgtgccctg
cggatcctaatcgtggattgggatgttcatcatggtaatggaactcagcacatatttgag
gatgaccctagtgtattatacgtgtccctgcaccggtatgaccgtggcactttcttcccc
atgggggatgagggtgccagtagccaagtaggccgagatgcaggtataggcttcactgtc
aatgtgccctggaatgggccccgcatgggtgatgctgattacctggctgcatggcatcgt
ctggtacttcccatcgcctatgagtttaacccagaactggtgctgatctcagctggcttt
gatgctgcacaaggggatccgctggggggctgccaagtaacaccggagggttatgcccac
ctcacccacctactgatgggccttgctggtggccgtattattcttattctagagggtgga
tacaatttggcatctatctctgagtctatggctgcctgcacccattccctccttggagac
ccaccaccccagcttactttgctgcgaccgccacagtcaggagccctggtttcaatcagt
gaggtcatccaagtccatcgcaaatactggcgcagtttgcggttgatgaaaatggaagac
aaggaagaatgctctagttctaggcttgtcatcaagaagttgcccccaacagccagtcct
gtatcagctaaggaaatgaccacaccgaaaggaaaggttcctgaagaaagcgtgaggaag
accatagcagcactacctgggaaagagtctactctaggccaggctaaatcaaagatggct
aaggctgtgcttgctcagggccagtcctcagaacaagctgctaagggaactacactggat
ctggctacctcaaaggagactgtgggaggagccacgacggacctgtgggcctcagcagct
gctcctgaaaacttccctaaccagaccacctctgtggaggctttgggagaaactgagcca
acgcctccagcctcgcatacaaacaagcagaccacaggggcttcacctctgcagggagtc
acggctcagcagtccctacagcttggggttctcagcactttggagctaagcagagaagca
gaggaagcccatgattctgaggagggcctgctaggggaagccgctggaggtcaggacatg
aacagcttgatgctgacacaaggatttggggactttaatacccaggatgtattttatgct
gtgaccccactatcctggtgtccccatttgatggcagtatgccccattcctgcagcaggc
ctagatgtgtcccaaccttgtaagacctgtggaacagtccaggagaactgggtgtgtctg
acttgctatcaggtgtactgcagtcgctatgtcaatgcccatatggtctgccaccatgaa
gcctctgaacacccgctggtcctcagctgtgttgacctgtctacctggtgttatgtctgt
caggcttatgtccaccacgaggatctccaagatgtgaagaacgctgcccaccagaacaag
tttggggaggacatgccccactcacactaa

  All links  
Ontology (6)   
   KEGG BRITE (6)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (49)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (41)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (11)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (9)   
DNA sequence (55)   
   RefSeq(nuc) (11)   
   GenBank (22)   
   EMBL (22)   
Protein domain (3)   
   Pfam (3)   
All databases (130)   

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